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Papers
The following papers have resulted from collaborations with the CBRG and either include CBRG
staff as authors or acknowledge CBRG support:
Contact details for the CBRG can be found at:
Papers
Nicola Floyd, Neil J. Oldham, Christopher J. Eyles, Stephen Taylor, Dimitry A. Filatov, Mark Brouard, and Benjamin G. Davis
Photo-Induced, Family-Specific, Site-Selective Cleavage of TIM-barrel Proteins
J. Am. Chem. Soc., 2009, 131 (35), pp.12518-12519
Mandeep Kaur, Sebastian Schmeier, Cameron R MacPherson, Oliver Hofmann, Winston A Hide, Stephen Taylor, Nick Willcox and Vladimir B Bajic
Prioritizing genes of potential relevance to diseases affected by sex hormones: An example of Myasthenia Gravis
BMC Genomics, 2008 Oct 9:481
Cynthia Wright, Mariola Edelmann, Kati diGleria, Simon Kollnberger, Holger Kramer, Simon McGowan, Kirsty McHugh, Stephen Taylor, Benedikt Kessler and Paul Bowness
Ankylosing Spondylitis Monocytes Show Upregulation of Proteins Involved in Inflammation and the Ubiquitin Proteasome Pathway
Annals of the Rheumatic Diseases, Oct 2008
Jill M. Brown, Joanne Green, Ricardo Pires das Neves, Helen A.C. Wallace, Andrew J.H. Smith, Jim Hughes, Nicki Gray, Steve Taylor, William G. Wood, Douglas R. Higgs, Francisco J. Iborra, and Veronica J. Buckle
Association between active genes occurs at nuclear speckles and is modulated by chromatin environment
J. Cell Biol., Sep 2008, 182: 1083 - 1097
Snyder LA, McGowan S,
Rogers M, Duro E, O'farrell E, Saunders NJ: The Repertoire of Minimal Mobile Elements in the Neisseria Species and Evidence That These
are Involved in Horizontal Gene Transfer in Other Bacteria.
Mol Biol Evol. 2007 24(12):2802-15
Boultwood J, Pellagatti A, Cattan H, Lawrie CH, Giagounidis A, Malcovati L, Porta MG, Jadersten M, Killick S, Fidler C, Cazzola M, Hellstrom-Lindberg E, Wainscoat JS.:
Gene expression profiling of CD34(+) cells in patients with the 5q- syndrome. Br J Haematol. 2007 139:578-89
Pellagatti A, Jadersten M, Forsblom AM, Cattan H, Christensson B, Emanuelsson EK, Merup M, Nilsson L, Samuelsson J, Sander B, Wainscoat JS, Boultwood J, Hellstrom-Lindberg E.:
Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients.
Proc Natl Acad Sci U S A. 2007, 104: 11406-11
Lawrie CH, Soneji S, Marafioti T, Cooper CD, Palazzo S, Paterson JC, Cattan H, Enver T, Mager R, Boultwood J, Wainscoat JS, Hatton CS: MicroRNA expression
distinguishes between germinal center B cell-like and activated B cell-like subtypes of diffuse large B cell lymphoma.
Int J Cancer. 2007, 121: 1156-61.
Simon McGowan and Steve Taylor (PDF). Poster:- Alternative DNA visualization using a GBrowse database
Functional Genomics & Systems Biology conference (Wellcome Trust Genome Campus in Hinxton, UK).
Rebekah
Whitehead, Tim Overton, Lori Snyder, Simon McGowan, Harry Smith, Jeff Cole, Nigel Saunders: The small FNR
regulon of Neisseria gonorrhoeae: comparison with the larger E. coli FNR regulon and interaction with the NarQ-NarP regulon.
BMC Genomics 2007, 8: 35
Nurfilza Ahmat, Lori Snyder, Simon McGowan, John Davies, and Nigel Saunders: Differing 'fever' responses in Neisseria
meningitidis and Neisseria gonorrhoeae leading to reduced expression of surface proteins likely to be immunological targets
(in preparation).
Michaël Bon, Simon McGowan, and Peter Cook: Many expressed genes in bacteria and yeast are transcribed only once per cell
cycle. The FASEB Journal 2006, 20: 1721-1723.
Simon McGowan et al: Description of a microarray targeted to genes important in mouse immune responses and differentiation.
(in preparation).
Carla Griffiths, Simon McGowan and William James: Bioinformatic analysis of RNA aptamers that bind to HIV-1BaL gp120. Oral
presentation at 158th SGM Meeting, University of Warwick, 3-6 April 2006
Acknowledgements
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Lemieux et al: Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture. 2009, PNAS 106(18):7559-64 |
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Jordan & Saunders: Host iron binding proteins acting as niche indicators for Neisseria meningitidis. PLoS One 2009, 4(4):e5198 |
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Herbert et al: A novel method of differential gene expression analysis using multiple cDNA libraries applied to the identification of tumour endothelial genes. BMC Genomics 2008, 9:153 |
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Ren et al: The structure and transcriptional analysis of a global regulator from Neisseria meningitidis. The Journal of Cell Biology 2007, 282(19):14655-64 |
| Malhas et al: Defects in lamin B1 expression or processing affect
interphase chromosome position and gene expression. The Journal of Cell Biology 2007, 176: 593-603. |
| Bentley
et al: Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18. Plos Genet 2007,
3. |
 |
| De Gobbi et al: A Regulatory SNP Causes a
Human Genetic Disease by Creating a New Transcriptional Promoter. Science 2006, 312: 1215-1217. |
| Snyder and Saunders: The majority of genes in
the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as virulence
genes. BMC Genomics 2006, 7: 128. |
| Snyder et
al: Comparative overview of the genomic and genetic differences between the pathogenic Neisseria strains and
species. Plasmid 2005, 54: 191-218. |
 |
| Hughes et
al: Annotation of cis-regulatory elements by identification, subclassification, and functional assessment of multispecies conserved
sequences. PNAS 2005, 102: 9830-9835 . |
| Snyder, Jarvis and
Saunders: Complete and variant forms of the 'gonococcal genetic island' in Neisseria meningitidis.
Microbiology 2005, 151: 4005-4013. |
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